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(2S,3R)-2-[[(2S)-6-Amino-2-[[(2S)-2-[[(2S)-2-Amino-3-Phenyl-Propanoyl] Amino]-3-(1H-Indol-3-Yl)Propanoyl]Amino]Hexanoyl]Amino]-3-Hydroxy-Buta Noic Acid CAS NO 91853-94-0
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CAS No.:91853-94-0
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
(2S,3R)-2-[[(2S)-6-Amino-2-[[(2S)-2-[[(2S)-2-Amino-3-Phenyl-Propanoyl] Amino]-3-(1H-Indol-3-Yl)Propanoyl]Amino]Hexanoyl]Amino]-3-Hydroxy-Buta Noic Acid is a complex, high-purity peptide derivative of significant interest in advanced pharmaceutical research and development. Its intricate structure, featuring multiple chiral centers and functional groups, makes it a critical building block for synthesizing novel bioactive compounds. This product is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require precise, high-quality intermediates for drug discovery and process development.
Application
- Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new therapeutic peptides and peptidomimetics.
- Drug Discovery: Used as a building block in combinatorial chemistry and high-throughput screening libraries to identify new lead compounds.
- Bioconjugation: Acts as a specialized linker or spacer molecule in the synthesis of antibody-drug conjugates (ADCs) and other targeted therapies.
- Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies and proteomics research due to its specific amino acid sequence.
- Fine Chemical Synthesis: Utilized in the multi-step synthesis of complex natural products and specialized organic molecules.
- Reference Standard: Provides a high-purity standard for analytical method development and quality control in pharmaceutical manufacturing.
Basic Information
| Item | Detail |
|---|---|
| Product Name | (2S,3R)-2-[[(2S)-6-Amino-2-[[(2S)-2-[[(2S)-2-Amino-3-Phenyl-Propanoyl] Amino]-3-(1H-Indol-3-Yl)Propanoyl]Amino]Hexanoyl]Amino]-3-Hydroxy-Buta Noic Acid |
| CAS No. | 91853-94-0 |
| Molecular Formula | C32H44N6O7 |
| Molecular Weight | 624.73 g/mol |
| Synonyms | Fmoc-Lys(Boc)-Trp-Phe-Thr-OH; Nα-Fmoc-Nε-Boc-L-tryptophyl-L-phenylalanyl-L-threonine; Fmoc-Lys(Boc)-Trp-Phe-Thr; Tetrapeptide Fmoc-Lys(Boc)-Trp-Phe-Thr; Boc-Lys(Fmoc)-Trp-Phe-Thr; (2S,3R)-2-[[(2S)-6-[[(1,1-Dimethylethoxy)carbonyl]amino]-2-[[(2S)-2-[[(2S)-2-amino-3-phenyl-1-oxopropyl]amino]-3-(1H-indol-3-yl)-1-oxopropyl]amino]-1-oxohexyl]amino]-3-hydroxybutanoic acid; 9H-Fluoren-9-ylmethyl (2S)-6-[[(1,1-dimethylethoxy)carbonyl]amino]-2-[[(2S)-2-[[(2S)-2-amino-3-phenyl-propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]hexanoyl-L-threoninate |
| EINECS | Contact for details |
Quality Control
Our (2S,3R)-2-[[(2S)-6-Amino-2-[[(2S)-2-[[(2S)-2-Amino-3-Phenyl-Propanoyl] Amino]-3-(1H-Indol-3-Yl)Propanoyl]Amino]Hexanoyl]Amino]-3-Hydroxy-Buta Noic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) with full traceability are provided, confirming compliance with specified parameters. We support cGMP and ISO guidelines for advanced intermediates.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Retention time matches reference standard |
| Purity (HPLC) | ≥ 98.0% |
| Chiral Purity | ≥ 99.0% |
| Water Content (KF) | ≤ 1.0% |
| Residue on Ignition | ≤ 0.5% |
| Heavy Metals | ≤ 20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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