Description

Tachyplesin CAS NO 118231-04-2 is a cationic antimicrobial peptide (AMP) originally isolated from the hemocytes of the Japanese horseshoe crab (*Tachypleus tridentatus*). This compound matters for its potent, broad-spectrum activity against bacteria, fungi, and certain viruses, making it a valuable molecule for research into novel anti-infective agents. It is primarily needed by researchers and developers in the pharmaceutical, biotechnology, and life science sectors for antimicrobial mechanism studies, drug discovery programs, and the development of new therapeutic and preservative formulations.

Application

• Antimicrobial Research: Investigation of its mechanism of action against Gram-positive and Gram-negative bacteria, fungi, and enveloped viruses.
• Drug Discovery & Development: Serving as a lead compound or structural template for designing novel peptide-based antibiotics and therapeutics.
• Biomaterial & Coating Development: Incorporation into medical device coatings, wound dressings, or surface treatments to impart antimicrobial properties.
• Immunology & Innate Immunity Studies: Used as a model peptide to study the role of host defense peptides in the innate immune response.
• Biochemical Reagent: Employed in laboratory studies of membrane disruption, pore formation, and peptide-lipid interactions.
• Preservative Research: Exploration of its potential as a natural preservative in cosmetic or specialty industrial applications.

Basic Information

Product Name	Tachyplesin
CAS No.	118231-04-2
Molecular Formula	C90H138N24O19
Molecular Weight	1828.2 g/mol
Synonyms	Tachyplesin I; Tachyplesin-1; Antimicrobial peptide Tachyplesin; Horseshoe crab antimicrobial peptide; Tachyplesin from *Tachypleus tridentatus*; TPN-I; TPN1
EINECS	Contact for details

Quality Control

Our Tachyplesin is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is characterized using advanced analytical techniques, including HPLC and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.