Description

Melanotan II is a synthetic peptide analog of the naturally occurring α-melanocyte-stimulating hormone (α-MSH). This compound is significant for its potent melanotropic activity, which stimulates melanogenesis and influences skin pigmentation. It is primarily utilized in research and development within the pharmaceutical and biotechnology sectors, focusing on dermatological and endocrinological studies.

Application

• Biomedical Research: Used as a key reference standard in studies investigating melanocortin receptor (MCR) pathways, particularly MC1R and MC4R.
• Pharmacological Development: Serves as a lead compound for developing novel therapeutics targeting pigmentation disorders and metabolic functions.
• Dermatological Studies: Employed in in vitro and in vivo models to understand mechanisms of skin tanning and photoprotection.
• Endocrinology Research: Investigated for its effects on appetite, sexual function, and energy homeostasis due to its action on central melanocortin receptors.
• Peptide Chemistry: Used as a model peptide in analytical method development, stability testing, and synthesis optimization.

Basic Information

Product Name	Melanotan II
CAS No.	121062-08-6
Molecular Formula	C₅₀H₆₈N₁₄O₁₀
Molecular Weight	1024.2 g/mol
Synonyms	Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH₂; Melanotan-2; MT-II; Melanotan 2; Bremelanotide (related metabolite); [Nle4, D-Phe7]-α-MSH; Afamelanotide analog; Melanocyte-stimulating hormone analog
EINECS	Contact for details

Quality Control

Our Melanotan II is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, mass spectrometry for identity confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing purity, peptide content, and related substances are available upon request to ensure compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Peptide Content	≥ 80.0%
Acetate Content (Titration)	≤ 15.0%
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.