Description

1-(n-(n-Acetylisoleucyl)-Tyrosyl)Amino-2-(4-Hydroxyphenyl)Ethylphosphonic Acid is a specialized synthetic peptide derivative that incorporates a phosphonic acid moiety, offering unique biochemical properties. This compound is significant for its potential role as a highly specific enzyme inhibitor or research probe, particularly in studies of signal transduction and metabolic pathways. It is primarily needed by pharmaceutical R&D and academic research institutions focused on developing novel therapeutic agents and studying protein-protein interactions.

Application

• Biochemical Research: Used as a potent and selective inhibitor for studying specific phosphatases or kinases in cellular signaling pathways.
• Pharmaceutical Development: Serves as a key intermediate or lead compound in the discovery of new drugs targeting metabolic disorders or bone-related diseases.
• Proteomics & Enzymology: Employed as a substrate analog or active-site probe to investigate enzyme mechanisms and specificity.
• Academic Research: Utilized in university and institutional labs for fundamental studies in medicinal chemistry and chemical biology.
• Peptide-Based Therapeutic Research: Investigated for its potential in creating novel peptide-drug conjugates with enhanced stability and targeting capabilities.

Basic Information

Product Name	1-(n-(n-Acetylisoleucyl)-Tyrosyl)Amino-2-(4-Hydroxyphenyl)Ethylphosphonic Acid
CAS No.	91796-92-8
Molecular Formula	C25H32N3O9P
Molecular Weight	549.51 g/mol
Synonyms	1-[(2S)-2-[[(2S)-2-Acetamido-3-methylpentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino-2-(4-hydroxyphenyl)ethylphosphonic Acid; Ac-Ile-Tyr(PO3H2)-NH-(4-Hydroxybenzyl)phosphonic Acid; N-Acetyl-Isoleucyl-O-Phosphono-Tyrosyl Amide Derivative; Phosphotyrosine Mimetic Peptide; Tyrosine Phosphonate Derivative; 91796-92-8; Ile-Tyr(P) Phosphonic Acid Analog
EINECS	Contact for details

Quality Control

Our 1-(n-(n-Acetylisoleucyl)-Tyrosyl)Amino-2-(4-Hydroxyphenyl)Ethylphosphonic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification (NMR, MS), to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with molecular structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.