Description

Glycine-2-13C-15N is a stable isotope-labeled analog of the fundamental amino acid glycine, specifically enriched with carbon-13 at the 2-position and nitrogen-15. This high-purity labeled compound is essential for advanced research requiring precise metabolic and structural analysis, offering unparalleled accuracy in tracing biochemical pathways. It is a critical reagent for scientists and manufacturers in pharmaceutical development, metabolic research, nuclear magnetic resonance (NMR) spectroscopy, and mass spectrometry (MS) applications.

Application

• Metabolic Pathway Tracing & Flux Analysis: Used as a stable isotope tracer in cell culture and in vivo studies to investigate glycine metabolism, one-carbon metabolism, and related biosynthetic pathways.
• NMR Spectroscopy Internal Standard: Serves as a quantitative internal standard and reference compound in 13C and 15N NMR experiments for protein structure determination and metabolomics.
• Mass Spectrometry (MS) Applications: Employed in LC-MS and GC-MS workflows as a labeled internal standard for the accurate quantification of glycine and related metabolites in complex biological samples.
• Pharmaceutical Research & Development: Critical in the development and testing of new drugs, particularly in pharmacokinetic (PK) and absorption, distribution, metabolism, and excretion (ADME) studies using isotope-labeled compounds.
• Biochemical Research & Proteomics: Used in protein labeling studies and for investigating amino acid transport and incorporation mechanisms.
• Nutritional Science Research: Applied in studies examining amino acid metabolism, protein synthesis, and nutritional biomarkers.

Basic Information

Product Name	Glycine-2-13C-15N
CAS No.	91795-59-4
Molecular Formula	13C¹H3¹⁵NO2
Molecular Weight	77.04 g/mol
Synonyms	Glycine-2-13C,15N; (2-13C,15N)Glycine; Aminoacetic-2-13C-15N acid; 2-Aminoacetic-2-13C-15N acid; Glycine (13C,15N); 13C,15N-Labeled Glycine; Stable Isotope Labeled Glycine; NSC 7601 (labeled)
EINECS	Contact for details

Quality Control

Our Glycine-2-13C-15N is produced under strict quality-controlled conditions to ensure the highest isotopic and chemical purity. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (atom % 13C and 15N), chemical purity, and specific analytical results. We adhere to stringent in-house specifications designed to meet the exacting requirements of research and pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0% (Chemical Purity)
Isotopic Enrichment (13C)	≥ 99 atom % 13C
Isotopic Enrichment (15N)	≥ 98 atom % 15N
Water Content (KF)	≤ 0.5 %
Residue on Ignition	≤ 0.1 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.