Description

Stigmatellin CAS NO 91682-96-1 is a potent, naturally occurring antibiotic and inhibitor of the mitochondrial cytochrome bc1 complex (Complex III). This compound is a critical biochemical tool for studying cellular respiration, electron transport chain function, and oxidative phosphorylation. It is essential for researchers in biochemistry, pharmacology, and molecular biology, as well as for industrial R&D teams focused on metabolic pathway analysis and antimicrobial discovery.

Application

• Biochemical Research: A primary tool for inhibiting the Qo site of the cytochrome bc1 complex in mitochondrial and bacterial electron transport chains.
• Cellular Respiration Studies: Used to investigate oxidative phosphorylation, ATP production, and the role of Complex III in metabolic pathways.
• Antimicrobial Mechanism Research: Serves as a model compound for studying the action of natural product antibiotics that target energy metabolism in pathogens.
• Pharmaceutical R&D: Employed in drug discovery programs targeting mitochondrial dysfunction or developing novel antimicrobial agents.
• Agricultural Chemistry: Potential use in research for developing new fungicides or bactericides that target energy production in pests.
• Academic & Industrial Laboratories: A standard reagent for enzymology assays and for validating the function of respiratory chain components.

Basic Information

Product Name	Stigmatellin
CAS No.	91682-96-1
Molecular Formula	C28H34O6
Molecular Weight	466.57 g/mol
Synonyms	Stigmatellin A; Antibiotic SL 84.0418; 2-[(2E,4E,6E,8E)-9-[(1S,2R,3S,4aS,8aS)-2,3-Dihydroxy-1,2,3,4,4a,8a-hexahydro-1,4a,5-trimethyl-7-(1-methylethenyl)-1-naphthalenyl]-3,7-dimethyl-2,4,6,8-nonatetraenoyl]-5,6-dimethoxy-3-methyl-1,4-benzoquinone; (1S,2R,3S,4aS,8aS)-1,2,3,4,4a,8a-Hexahydro-2,3-dihydroxy-1,4a,5-trimethyl-7-(1-methylethenyl)-1-naphthaleneacetic Acid (2E,4E,6E,8E)-9-Oxo-3,7-dimethyl-2,4,6,8-nonatetraenyl Ester
EINECS	Contact for details

Quality Control

Our Stigmatellin is produced and handled under strict quality protocols to ensure batch-to-batch consistency and reliability for critical research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity verification and structural confirmation via spectroscopic methods. A Certificate of Analysis (COA) detailing identity, purity, and specific test results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Yellow to orange powder or crystals
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, ethanol, methanol; insoluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.