Description

(1R,2R)-1,2-Dihydro-7-Methylbenz[A]Anthracene-1,2-Diol is a high-purity, stereospecific dihydrodiol derivative of a methylated benz[a]anthracene. This compound is of significant value as a key chiral intermediate or reference standard in advanced organic synthesis and analytical research. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in the study of polycyclic aromatic hydrocarbon (PAH) metabolism, carcinogenesis, or the development of targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block for the synthesis of complex molecules in drug discovery programs.
• Biochemical Research: Used as a substrate or metabolite analog in enzymatic studies related to cytochrome P450 metabolism and DNA adduct formation.
• Analytical Reference Standard: Employed as a high-purity calibrant in HPLC, LC-MS, or GC-MS methods for quantifying PAH metabolites in environmental or biological samples.
• Toxicology Studies: Acts as a precise chemical tool for investigating the mechanisms of PAH-induced toxicity and carcinogenicity.
• Organic Synthesis: Utilized in asymmetric synthesis and catalysis research due to its defined stereochemistry.

Basic Information

Product Name	(1R,2R)-1,2-Dihydro-7-Methylbenz[A]Anthracene-1,2-Diol
CAS No.	91327-05-8
Molecular Formula	C19H16O2
Molecular Weight	276.33 g/mol
Synonyms	(1R,2R)-7-Methylbenz[a]anthracene-1,2-dihydrodiol; (1R,2R)-7-Methylbenz[a]anthracene 1,2-diol; 7-Methylbenz[a]anthracene (1R,2R)-dihydrodiol; (+)-(1R,2R)-1,2-Dihydroxy-1,2-dihydro-7-methylbenz[a]anthracene; 7-MBA (1R,2R)-dihydrodiol; 7-Methyl-BA trans-1,2-dihydrodiol (R,R enantiomer)
EINECS	Contact for details

Quality Control

Our (1R,2R)-1,2-Dihydro-7-Methylbenz[A]Anthracene-1,2-Diol is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure high chemical and stereochemical purity suitable for research applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, cool place. For long-term storage, consider storing under inert atmosphere at lower temperatures (-20°C) to maximize stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.