Description

N,N'-Ethylenediamineditetrodotoxin is a specialized derivative of the potent neurotoxin tetrodotoxin, modified with an ethylenediamine bridge. This compound is of significant interest in advanced biochemical and pharmacological research due to its potential for targeted activity and as a tool for studying sodium ion channels. It is primarily utilized by research institutions and pharmaceutical development laboratories focused on neuroscience, pain management, and novel therapeutic agent discovery.

Application

• Neuroscience Research: As a high-affinity ligand for voltage-gated sodium channels (VGSCs) for studying channel function and neuronal signaling.
• Pharmacological Tool Compound: Used in the development and screening of new analgesic and anesthetic agents.
• Biochemical Assays: Employed in competitive binding assays and receptor studies to understand toxin-receptor interactions.
• Toxicology Studies: Serves as a reference standard in the analysis of marine and pufferfish toxins.
• Drug Discovery Platforms: Utilized in structure-activity relationship (SAR) studies to design novel neuroactive compounds with modified potency or selectivity.

Basic Information

Product Name	N,N'-Ethylenediamineditetrodotoxin
CAS No.	91260-89-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Ethylenediamine tetrodotoxin derivative; Tetrodotoxin ethylenediamine adduct; TTX-EDA derivative; 4,9-Anhydro-10-[(2-aminoethyl)amino]-12-(hydroxymethyl)-2,6,8,12-tetrahydroxy-6-(hydroxymethyl)-2-imino-5,7:9,11-dimethano-5H-[1,3]dioxocino[5,4-d]pyrimidin-10-ium (IUPAC-based); Sodium channel blocker derivative; Neurotoxin research compound
EINECS	Contact for details

Quality Control

Our N,N'-Ethylenediamineditetrodotoxin is produced and handled under strict quality management protocols suitable for research applications. Each batch undergoes comprehensive analytical testing, including purity assay and identity confirmation, to ensure consistency and reliability. A detailed Certificate of Analysis (COA) is provided with every shipment to support your research integrity and documentation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Loss on Drying	≤ 2.0%
Single Largest Impurity (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.