Description

4-Ethoxy-1-Naphthalenesulfonyl Chloride (Saltdata: Free) is a specialized sulfonyl chloride derivative, a key reactive intermediate in advanced organic synthesis. Its value lies in its role as a versatile electrophile for introducing the 4-ethoxy-1-naphthalenesulfonyl moiety, enabling the creation of sulfonamides, sulfonate esters, and other functionalized compounds. This high-purity building block is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries developing novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a naphthalene-based sulfonamide or sulfonate functional group.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the sulfonyl chloride group acts as a key linkage.
• Dye and Pigment Manufacturing: Serves as a building block for synthesizing sulfonated dyes and colorants with specific light-fastness and solubility properties.
• Polymer Modification: Employed to introduce sulfonyl groups into polymer chains, altering properties like solubility, thermal stability, or reactivity for advanced materials.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic pathways and creating compound libraries for screening.
• Ligand and Catalyst Preparation: Used to functionalize ligands or catalyst scaffolds with the sulfonyl group, modifying their electronic properties and metal-binding affinity.

Basic Information

Product Name	4-Ethoxy-1-Naphthalenesulfonyl Chloride (Saltdata: Free)
CAS No.	91222-55-8
Molecular Formula	C₁₂H₁₁ClO₃S
Molecular Weight	270.73 g/mol
Synonyms	1-Naphthalenesulfonyl chloride, 4-ethoxy-; 4-Ethoxynaphthalene-1-sulfonyl chloride; 4-Ethoxy-1-naphthalenesulfonyl chloride; 4-Ethoxynaphthalenesulfonyl chloride; 1-(Chlorosulfonyl)-4-ethoxynaphthalene; 4-Ethoxy-1-naphthylsulfonyl chloride; 4-Ethoxynaphthalene-1-sulphonyl chloride; 4-Ethoxy-1-naphthalenesulphonyl chloride
EINECS	Contact for details

Quality Control

Our 4-Ethoxy-1-Naphthalenesulfonyl Chloride is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets exacting standards for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent hydrolysis. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.