Description

5,6-Dihydroxyprostaglandin E1 is a high-purity, biologically active prostaglandin analog. This compound is valued for its role as a key intermediate and reference standard in advanced pharmaceutical research and development. It is primarily utilized by researchers and manufacturers in the life sciences sector focusing on cardiovascular, inflammatory, and metabolic pathways.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel therapeutic agents targeting prostaglandin receptors.
• Biochemical Research: Used as a reference standard and active compound in studies of eicosanoid biology, signal transduction, and cellular regulation.
• Drug Discovery & Development: Employed in high-throughput screening (HTS) and preclinical studies to investigate efficacy and mechanism of action for new drug candidates.
• Analytical Standard: Serves as a certified reference material (CRM) for quality control and method validation in analytical laboratories using HPLC, LC-MS, or GC-MS.
• Cell Culture & In Vitro Studies: Applied in experimental models to study its effects on vasodilation, platelet aggregation, and inflammatory responses.

Basic Information

Product Name	5,6-Dihydroxyprostaglandin E1
CAS No.	90817-53-1
Molecular Formula	C₂₀H₃₄O₆
Molecular Weight	370.48 g/mol
Synonyms	5,6-Di-OH PGE1; 5,6-Dihydroxy-PGE1; 9,15-Dihydroxy-11-oxoprosta-5,13-dien-1-oic acid (5Z,13E); Prostaglandin E1 derivative; DH-PGE1; 5,6-Dihydroxy alprostadil
EINECS	Contact for details

Quality Control

Our 5,6-Dihydroxyprostaglandin E1 is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including identity confirmation by spectroscopic methods and purity assessment by chromatographic techniques, to ensure it meets the stringent requirements for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.