Description

Diprotin A is a highly specific and potent dipeptidyl peptidase IV (DPP-IV) inhibitor, widely recognized for its role in biochemical and pharmacological research. This compound is crucial for studying enzyme kinetics, insulin secretion pathways, and the degradation of incretin hormones like GLP-1. It serves as an essential research tool for scientists and manufacturers in the pharmaceutical, biotechnology, and academic sectors who are developing novel therapeutics for metabolic disorders such as type 2 diabetes.

Application

• Biochemical Research: Used as a selective inhibitor to study the structure, function, and inhibition mechanisms of dipeptidyl peptidase IV (DPP-IV) in vitro.
• Pharmaceutical R&D: A critical reference standard and intermediate in the discovery and development of new anti-diabetic drugs targeting the DPP-4 enzyme.
• Metabolic Studies: Employed in laboratory experiments to investigate the regulation of blood glucose levels and the role of incretin hormones.
• Enzyme Assay Development: Serves as a control compound in high-throughput screening (HTS) assays to identify and validate new DPP-IV inhibitors.
• Academic Research: Utilized in university and institutional labs for fundamental research on peptide metabolism and signal transduction.
• Quality Control: Acts as a purity standard for the manufacturing and quality assurance of related peptide-based active pharmaceutical ingredients (APIs).

Basic Information

Item	Detail
Product Name	Diprotin A
CAS No.	90614-48-5
Molecular Formula	C14H26N4O4
Molecular Weight	314.38 g/mol
Synonyms	Ile-Pro-Ile; Isoleucyl-prolyl-isoleucine; DPP-IV Inhibitor I; H-Ile-Pro-Ile-OH; N-Isoleucyl-L-prolyl-L-isoleucine; Dipeptidyl Peptidase-4 Inhibitor; Pro-Ile-Pro; (S)-1-((S)-2-((S)-2-Amino-3-methylpentanamido)pyrrolidine-1-carbonyl)-3-methylpentylamine
EINECS	Contact for details

Quality Control

Our Diprotin A is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent controls for residual solvents and heavy metals. Certificates of Analysis (COA) documenting full compliance with in-house specifications are provided to ensure traceability and reliability for your critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	<10 ppm
Biological Activity (DPP-IV Inhibition)	IC50 ≤ 5 µM

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.