Description

4-Methoxy-2,3-Dimethylbenzenesulfonyl Chloride is a high-purity, versatile sulfonyl chloride derivative essential for advanced organic synthesis. Its primary value lies in its role as a key electrophilic building block for introducing the sulfonamide functional group, which is critical in the development of active pharmaceutical ingredients and specialty agrochemicals. This compound is particularly sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the manufacture of novel herbicides, fungicides, and plant growth regulators that require the sulfonamide moiety for bioactivity.
• Dye and Pigment Manufacturing: Serves as a key reactant for producing sulfonated dyes and colorants with enhanced solubility and fastness properties.
• Polymer Chemistry: Employed as a monomer or cross-linking agent in the production of specialty polymers, such as polyelectrolytes and ion-exchange resins.
• Chemical Research & Development: A valuable reagent for medicinal chemistry, process chemistry, and method development in academic and industrial laboratories.
• Ligand and Catalyst Design: Used to synthesize specialized ligands for metal complexes and organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	4-Methoxy-2,3-Dimethylbenzenesulfonyl Chloride
CAS No.	90416-51-6
Molecular Formula	C9H11ClO3S
Molecular Weight	234.70 g/mol
Synonyms	2,3-Dimethyl-4-methoxybenzenesulfonyl chloride; 4-Methoxy-2,3-dimethylbenzene-1-sulfonyl chloride; 1-(Chlorosulfonyl)-4-methoxy-2,3-dimethylbenzene; 2,3-Dimethylanisole-4-sulfonyl chloride; 4-Methoxy-2,3-dimethylphenylsulfonyl chloride; AS-23470; Benzenesulfonyl chloride, 4-methoxy-2,3-dimethyl-
EINECS	Contact for details

Quality Control

Every batch of 4-Methoxy-2,3-Dimethylbenzenesulfonyl Chloride is manufactured and tested under a strict quality management system. We guarantee high chemical purity and consistency, with comprehensive testing including identity confirmation (IR, NMR), assay (HPLC), and impurity profiling. A detailed Certificate of Analysis (COA) is provided with each shipment to ensure full traceability and compliance with your internal specifications and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.