Description

9-Enol-Prostaglandin E2 Methyl Ester Trimethylsilyl Ether is a key synthetic intermediate and protected derivative of Prostaglandin E2 (PGE2). This compound is of significant value in pharmaceutical research and development, particularly for the synthesis of prostaglandin analogs and other bioactive molecules. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in advanced organic synthesis and drug discovery programs.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of Prostaglandin E2 analogs and related therapeutic agents.
• Biochemical Research: Used as a protected standard or precursor in studies investigating prostaglandin biosynthesis, metabolism, and signaling pathways.
• Medicinal Chemistry: Serves as a versatile scaffold for the development of novel anti-inflammatory, cardiovascular, and gastrointestinal drugs.
• Fine Chemical Synthesis: Employed in the production of high-value, complex organic molecules requiring specific stereochemistry and functional group protection.
• Reference Standard: Can be used as a chromatographic reference material in analytical method development for prostaglandin analysis.

Basic Information

Product Name	9-Enol-Prostaglandin E2 Methyl Ester Trimethylsilyl Ether
CAS No.	90293-03-1
Molecular Formula	C27H48O5Si
Molecular Weight	480.76 g/mol
Synonyms	PGE2 Methyl Ester 9-Enol TMS Ether; Methyl (5Z,9α,11α,13E,15S)-9,11,15-Trihydroxy-16-[(trimethylsilyl)oxy]prosta-5,13-dien-1-oate; 9-Enol TMS Ether of PGE2 Methyl Ester; Prostaglandin E2 Methyl Ester 9-Enol Trimethylsilyl Ether; 9-Enol-PGE2-ME-TMS; 9-Enol TMS PGE2 Methyl Ester; (15S)-9,11,15-Trihydroxy-16-[(trimethylsilyl)oxy]prosta-5,13-dien-1-oic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our 9-Enol-Prostaglandin E2 Methyl Ester Trimethylsilyl Ether is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing purity (typically by HPLC), identity confirmation (by IR, NMR), and impurity profiles are available for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere when not in use to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.