Description

6-Chloro-2,5-Difluoro-Toluene is a halogenated aromatic compound that serves as a versatile and critical building block in advanced organic synthesis. Its value lies in the strategic positioning of chlorine and fluorine atoms on the toluene backbone, enabling precise chemical modifications. This intermediate is primarily needed by the pharmaceutical and agrochemical industries for the development of active ingredients, as well as by research institutions and material science companies.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of complex drug molecules, particularly in the development of active pharmaceutical ingredients (APIs) with specific biological activity.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the difluoro and chloro substituents contribute to efficacy and stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for creating fluorinated organic compounds used in electronic displays and optoelectronic devices.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to introduce functionalized aryl groups.
• Chemical Research & Development: Utilized in academic and industrial R&D labs for exploring new synthetic pathways and novel fluorinated compounds.
• Specialty Chemical Manufacturing: Acts as a precursor for dyes, pigments, and other performance chemicals requiring specific halogenated aromatic structures.

Basic Information

Product Name	6-Chloro-2,5-Difluoro-Toluene
CAS No.	90292-64-1
Molecular Formula	C7H5ClF2
Molecular Weight	162.56 g/mol
Synonyms	2,5-Difluoro-6-chlorotoluene; 1-Chloro-2,5-difluoro-4-methylbenzene; 4-Chloro-2,5-difluorotoluene; Toluene, 6-chloro-2,5-difluoro-; 2-Chloro-1,4-difluoro-5-methylbenzene; 6-Chloro-2,5-difluoromethylbenzene; 2,5-Difluoro-6-chloro-1-methylbenzene
EINECS	Contact for details

Quality Control

Our 6-Chloro-2,5-Difluoro-Toluene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0% (Area %)
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.