Description

5-Methyl-1-Benzothiophene-2-Sulfonyl Chloride is a key sulfonyl chloride derivative used as a versatile building block in advanced organic synthesis. This compound is particularly valued for its role in introducing the 5-methylbenzothiophene-2-sulfonyl moiety, a crucial functional group in medicinal chemistry and materials science. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, particularly those targeting enzyme inhibition or receptor modulation.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the benzothiophene scaffold for bioactivity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialized polymers, dyes, and organic electronic materials.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes and labeling reagents for studying biological processes.
• Sulfonamide Library Synthesis: A high-value building block for combinatorial chemistry and the generation of diverse sulfonamide-based compound libraries for screening.

Basic Information

Item	Details
Product Name	5-Methyl-1-Benzothiophene-2-Sulfonyl Chloride
CAS No.	90273-30-6
Molecular Formula	C9H7ClO2S2
Molecular Weight	246.73 g/mol
Synonyms	5-Methylbenzo[b]thiophene-2-sulfonyl chloride; 2-Thiophenesulfonyl chloride, 5-methyl-1-benzothiophene-; 5-Methyl-1-benzothiophene-2-sulfonylchloride; 5-Methylbenzothiophene-2-sulfonyl chloride; 5-Methylbenzo[b]thiophene-2-sulfonylchloride; 90273-30-6; 5-Methyl-1-benzothiophene-2-sulphonyl chloride
EINECS	Contact for details

Quality Control

Our 5-Methyl-1-Benzothiophene-2-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from moisture. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.