Description

Zymosan A is a purified, insoluble polysaccharide complex derived from yeast cell walls, widely recognized for its immunostimulatory properties. Its primary value lies in its ability to reliably activate the complement system and stimulate phagocytic cells, making it an essential research tool in immunology and inflammation studies. This product is critical for researchers and manufacturers in the life sciences, pharmaceutical development, and diagnostic reagent production who require a consistent and high-quality ligand for pattern recognition receptors.

Application

• Immunological Research: Standard ligand for in vitro and in vivo studies of innate immune response, macrophage activation, and Toll-like receptor 2 (TLR2) signaling.
• Complement System Studies: Used to activate the alternative complement pathway in serum for research into inflammatory diseases and immune complex disorders.
• Phagocytosis Assays: Employed as a target particle to measure the phagocytic capacity and efficiency of neutrophils, macrophages, and other professional phagocytes.
• Inflammation Modeling: Key component in establishing experimental models of peritonitis, arthritis, and other inflammatory conditions in animal studies.
• Biomaterial & Adjuvant Development: Investigated for its potential in vaccine adjuvants and as a surface modifier to study immune cell interactions with biomaterials.
• Diagnostic Reagent Manufacturing: Serves as a quality control standard or active component in diagnostic kits designed to assess immune function.

Basic Information

Product Name	Zymosan A
CAS No.	9010-72-4
Molecular Formula	Complex polysaccharide (primarily β-glucan and mannan)
Molecular Weight	High molecular weight complex
Synonyms	Zymosan; Zymosan from Saccharomyces cerevisiae; Yeast Cell Wall Polysaccharide; β-Glucan-Mannan Complex; Complement Activator (Particulate); Phagocytosis Stimulant; TLR2 Ligand
EINECS	Contact for details

Quality Control

Our Zymosan A is produced under a stringent quality management system to ensure batch-to-batch consistency and biological activity. Each lot is characterized for its ability to activate complement and stimulate phagocytes. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing specifications for identity, purity, and functional activity, supporting compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	Off-white to light tan powder
Identification (IR)	Conforms to reference spectrum
Functional Activity (Phagocytosis)	Meets internal bioassay standard
Complement Activation	Activates alternative pathway in control serum
Solubility	Insoluble in water and common organic solvents
Loss on Drying	< 8.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.