Description

Tsh CAS NO 9002-71-5 is a high-purity grade of the polypeptide hormone Thyrotropin (TSH), also known as Thyroid-Stimulating Hormone. This compound is critical for research and development in endocrinology and diagnostic applications, where precise biological activity is required. It is essential for pharmaceutical researchers, diagnostic kit manufacturers, and academic institutions studying thyroid function and related metabolic disorders.

Application

• Diagnostic Reagent Manufacturing: A key component in immunoassay kits for the quantitative measurement of TSH levels in human serum, vital for diagnosing thyroid disorders like hypothyroidism and hyperthyroidism.
• Biomedical Research: Used in cell culture and animal studies to investigate thyroid gland physiology, hormone regulation pathways, and the mechanisms of action of thyroid hormones.
• Pharmaceutical Development: Serves as a reference standard in the development and quality control of biopharmaceuticals targeting the thyroid axis.
• Clinical Calibration: Employed as a calibrator or control material to ensure the accuracy and precision of automated clinical chemistry analyzers in hospital laboratories.
• Endocrinology Studies: Fundamental for in vitro studies exploring feedback loops within the hypothalamic-pituitary-thyroid (HPT) axis.

Basic Information

Product Name	Tsh
CAS No.	9002-71-5
Molecular Formula	C990H1527N263O299S21 (Approximate, for alpha subunit)
Molecular Weight	~28,000 Da (Glycoprotein, varies with glycosylation)
Synonyms	Thyrotropin; Thyroid-Stimulating Hormone; TSH; Thyrotropic Hormone; Thyrotrophin; Thyrotropic Hormone; Human Thyroid-Stimulating Hormone; hTSH; Thyrotropin Alfa; Thyrogen® (brand name variant).
EINECS	Contact for details

Quality Control

Our Tsh (CAS 9002-71-5) is produced and tested under stringent quality management systems. Each batch is characterized for identity, purity, and biological potency to ensure consistency for critical research and diagnostic applications. Certificates of Analysis (COA) detailing specifications such as purity by HPLC, bioactivity via cell-based assays, and endotoxin levels are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store frozen at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature before opening to minimize moisture uptake. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to standard
Purity (HPLC)	≥ 95.0%
Biological Activity	≥ 80% of reference standard
Endotoxin	< 10.0 EU/mg
Moisture (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.