Description

Corticotropin CAS NO 9002-60-2 is a polypeptide hormone, also known as adrenocorticotropic hormone (ACTH), which plays a critical role in stimulating the adrenal cortex to produce and release cortisol. This compound is essential for research and development in endocrinology and metabolic studies. It is primarily utilized by the pharmaceutical, biotechnology, and life science research sectors for diagnostic applications, therapeutic development, and advanced biochemical investigations.

Application

• Pharmaceutical Active Ingredient: Used in the formulation of diagnostic agents for assessing adrenal gland function (ACTH stimulation test).
• Biomedical Research: Serves as a key reagent in studying the hypothalamic-pituitary-adrenal (HPA) axis, stress response, and corticosteroid synthesis.
• Reference Standard: Employed as a high-purity standard in analytical laboratories for quality control and method validation.
• Therapeutic Development: Investigated for potential use in treating certain inflammatory and autoimmune conditions.
• Cell Culture & In Vitro Studies: Applied in research to study its effects on steroidogenesis in adrenal cell cultures.

Basic Information

Product Name	Corticotropin
CAS No.	9002-60-2
Molecular Formula	C207H308N56O58S
Molecular Weight	4541.1 g/mol (approx., for the 39-amino acid form)
Synonyms	Adrenocorticotropic Hormone; ACTH; Adrenocorticotropin; Corticotrophin; β-Corticotropin; Cosyntropin (synthetic fragment); Seractide; Tetracosactide; NDC 55566-1001-1
EINECS	Contact for details

Quality Control

Our Corticotropin is produced and tested under strict quality management systems. Each batch undergoes comprehensive analysis to ensure identity, purity, and biological activity, meeting high standards for research and pharmaceutical use. Certificates of Analysis (COA) detailing specifications such as potency (IU/mg), purity by HPLC, and peptide content are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature or as specified on the label. Due to its hygroscopic (moisture-sensitive) nature, the product should be kept in a dry environment. For long-term stability, storage at -20°C is recommended.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	≥ 95.0%
Potency (Bioassay)	≥ 80 IU/mg
Water Content (KF)	≤ 5.0%
Peptide Content (N)	≥ 80.0%
Biological Activity	Stimulates corticosteroid production in vitro

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.