Description

5'-Deoxy-S-Adenosyl-L-Homocysteine is a key biochemical intermediate and a potent inhibitor of S-adenosyl-L-homocysteine hydrolase. This compound is critical for research into methylation processes, epigenetics, and enzyme kinetics. It is primarily utilized by pharmaceutical R&D teams, academic biochemistry laboratories, and manufacturers of diagnostic reagents for metabolic studies.

Application

• Biochemical Research: As a standard and inhibitor in studies of transmethylation reactions and one-carbon metabolism.
• Enzymology: Used to investigate the mechanism and inhibition of S-adenosylhomocysteine hydrolase (SAHH).
• Pharmaceutical Development: Serves as a reference compound and potential starting material in the development of antiviral and anticancer therapeutics targeting methylation pathways.
• Diagnostic Reagents: Employed in the formulation of kits and assays for measuring methyltransferase activity and related metabolic disorders.
• Epigenetics Studies: A vital tool for researching the role of SAM/SAH ratios in DNA and histone methylation.

Basic Information

Product Name	5'-Deoxy-S-Adenosyl-L-Homocysteine
CAS No.	979-92-0
Molecular Formula	C14H20N6O4S
Molecular Weight	368.41 g/mol
Synonyms	5'-Deoxy-S-adenosyl-L-homocysteine; 5'-Deoxy-S-adenosylhomocysteine; 5'-dAdoHcy; 5'-Deoxyadenosylhomocysteine; SAH analog; S-(5'-Deoxyadenosin-5'-yl)-L-homocysteine; 5'-Deoxy-SAH; L-5'-Deoxy-S-adenosylhomocysteine
EINECS	Contact for details

Quality Control

Our 5'-Deoxy-S-Adenosyl-L-Homocysteine is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive (store away from light). For long-term storage, consider desiccant and under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content	≤ 5.0% (KF)
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.