Description

4-Methoxybenzenesulfonyl Chloride is a versatile and high-purity sulfonyl chloride derivative, essential as a key building block in advanced organic synthesis. Its primary value lies in its reactivity as a sulfonylation agent, enabling the introduction of the 4-methoxybenzenesulfonyl moiety to create compounds with specific functionalities. This intermediate is critically needed by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial reagent in the synthesis of sulfonamide-based drugs, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the production of modern herbicides, fungicides, and pesticides that require sulfonyl group chemistry.
• Polymer Chemistry: Serves as a monomer or modifier in the creation of specialty polymers and resins with tailored properties.
• Dye and Pigment Manufacturing: Acts as an intermediate for synthesizing sulfonated dyes and colorants.
• Chemical Research & Development: Employed in academic and industrial labs for method development and creating novel chemical entities.
• Peptide Modification: Used to protect or modify amino acid side chains during peptide synthesis.

Basic Information

Product Name	4-Methoxybenzenesulfonyl Chloride
CAS No.	98-68-0
Molecular Formula	C7H7ClO3S
Molecular Weight	206.65 g/mol
Synonyms	p-Anisylsulfonyl chloride; 4-Methoxybenzene-1-sulfonyl chloride; p-Methoxybenzenesulfonyl chloride; Anisolesulfonyl chloride; 4-Methoxybenzenesulphonyl chloride; 4-Methoxy-phenylsulfonyl chloride; 98-68-0; NSC 406916
EINECS	202-692-8

Quality Control

Our 4-Methoxybenzenesulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	40 - 44 °C
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.