Description

4-Chlorobenzenesulfonyl Chloride is a versatile and highly reactive organosulfur compound, serving as a critical building block in advanced organic synthesis. Its primary value lies in its dual functionality as both an electrophilic sulfonylating agent and a precursor for sulfonamide derivatives, enabling the creation of complex molecular architectures. This intermediate is essential for research and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to develop active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drugs, including diuretics, antibacterial agents, and COX-2 inhibitors.
• Agrochemical Synthesis: Building block for manufacturing herbicides, fungicides, and plant growth regulators that require the sulfonyl chloride moiety.
• Dyestuff and Pigment Production: Used in the synthesis of sulfonated dyes and optical brighteners.
• Polymer Chemistry: Monomer or modifying agent for creating specialty polymers with specific sulfone or sulfonamide linkages.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new reaction pathways and creating novel sulfonyl-containing compounds.
• Liquid Crystal & Electronic Materials: Intermediate in the production of sulfone-based compounds used in advanced material science applications.

Basic Information

Product Name	4-Chlorobenzenesulfonyl Chloride
CAS No.	98-60-2
Molecular Formula	C6H4Cl2O2S
Molecular Weight	211.06 g/mol
Synonyms	p-Chlorobenzenesulfonyl Chloride; 4-Chlorophenylsulfonyl Chloride; Benzenesulfonyl Chloride, 4-chloro-; 1-Chloro-4-(chlorosulfonyl)benzene; NSC 406908; PCSC; 4-CBSC
EINECS	202-686-1

Quality Control

Our 4-Chlorobenzenesulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment, ensuring full traceability and compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed to prevent decomposition from atmospheric moisture. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or lumps
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	50 - 54 °C
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.