Description

4-Bromobenzenesulfonyl Chloride is a versatile and highly reactive organosulfur compound primarily used as a key sulfonylation reagent and synthetic building block. Its value lies in its ability to introduce the 4-bromobenzenesulfonyl moiety, a crucial functional group for modifying molecular properties and creating complex chemical architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of sulfonamide-based drugs, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the production of modern herbicides, fungicides, and pesticides that require specific sulfonyl group chemistry.
• Polymer Modification: Serves as a monomer or cross-linking agent to impart specific thermal, chemical, or solubility properties to advanced polymers.
• Dye and Pigment Manufacturing: Acts as an intermediate in the synthesis of sulfonated dyes and colorants for textiles and plastics.
• Material Science Research: Employed in creating novel organic frameworks, liquid crystals, and other functional materials.
• Chemical Derivatization Agent: Used in analytical chemistry to derivative compounds for detection or separation purposes (e.g., in HPLC).

Basic Information

Product Name	4-Bromobenzenesulfonyl Chloride
CAS No.	98-58-8
Molecular Formula	C6H4BrClO2S
Molecular Weight	255.52 g/mol
Synonyms	p-Bromobenzenesulfonyl chloride; 4-Bromobenzene-1-sulfonyl chloride; Benzenesulfonyl chloride, 4-bromo-; 1-Bromo-4-(chlorosulfonyl)benzene; NSC 406908; BSC; 4-Bromophenylsulfonyl chloride
EINECS	202-683-6

Quality Control

Our 4-Bromobenzenesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our production adheres to cGMP principles where applicable, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases, oxidizing agents, and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	73 - 77 °C
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.