Description

1-(2-Chloro-Pyridin-4-Yl)-2,2,2-Trifluoro-Ethanone is a high-purity trifluoromethyl ketone derivative featuring a chloropyridine moiety, serving as a critical advanced pharmaceutical intermediate. Its core value lies in enabling the synthesis of complex bioactive molecules, particularly in the development of novel agrochemicals and active pharmaceutical ingredients (APIs). This compound is essential for research and manufacturing chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate a reactive trifluoroacetyl group into heterocyclic systems.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides that require the chloropyridine-trifluoromethyl ketone pharmacophore.
• Chemical Research & Development: Serves as a versatile precursor for novel heterocyclic compounds in academic and industrial R&D laboratories.
• Ligand & Catalyst Development: Utilized in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions.
• Material Science Precursor: Potential intermediate for creating functionalized polymers or organic electronic materials.

Basic Information

Product Name	1-(2-Chloro-Pyridin-4-Yl)-2,2,2-Trifluoro-Ethanone
CAS No.	898784-96-8
Molecular Formula	C7H3ClF3NO
Molecular Weight	209.55 g/mol
Synonyms	2-Chloro-4-(trifluoroacetyl)pyridine; 4-Acetyl-2-chloropyridine, 2,2,2-trifluoro-; 1-(2-Chloro-4-pyridinyl)-2,2,2-trifluoroethanone; 2-Chloro-4-pyridyl trifluoromethyl ketone; 2-Chloro-4-trifluoroacetylpyridine; 4-(Trifluoroacetyl)-2-chloropyridine; 2-Chloropyridin-4-yl trifluoromethyl ketone; 1-(2-Chloropyridin-4-yl)-2,2,2-trifluoroethan-1-one
EINECS	Contact for details

Quality Control

Our 1-(2-Chloro-Pyridin-4-Yl)-2,2,2-Trifluoro-Ethanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; ensure containers are kept tightly sealed to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.