Description

6-(3,4-Difluorophenyl)-3-Pyridinecarbaldehyde is a high-purity, multi-functional aromatic aldehyde building block. This compound is valued for its unique molecular architecture, which combines a pyridine core with a difluorophenyl substituent, making it a critical intermediate in advanced synthetic pathways. It is primarily sought after by research institutions and industrial R&D departments engaged in the development of novel pharmaceuticals, agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and kinase inhibitors.
• Agrochemical Research: Serves as a versatile scaffold for developing new herbicides, fungicides, and insecticides, leveraging the bioactivity of the difluorophenyl and pyridine motifs.
• Ligand and Catalyst Synthesis: Used in the preparation of specialized ligands for transition metal catalysis and organocatalysts due to its aldehyde functionality and electron-deficient heterocycle.
• Material Science: Employed in the creation of organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs) where its rigid, planar structure and fluorine atoms can tune electronic properties.
• Chemical Biology Probes: Acts as a building block for fluorescent tags, photoaffinity labels, and other molecular probes used in biochemical research and diagnostics.

Basic Information

Product Name	6-(3,4-Difluorophenyl)-3-Pyridinecarbaldehyde
CAS No.	898404-54-1
Molecular Formula	C12H7F2NO
Molecular Weight	219.19 g/mol
Synonyms	3-Pyridinecarboxaldehyde, 6-(3,4-difluorophenyl)-; 6-(3,4-Difluorophenyl)nicotinaldehyde; 6-(3,4-Difluorophenyl)pyridine-3-carbaldehyde; 3-Formyl-6-(3,4-difluorophenyl)pyridine; 898404-54-1; 6-(3,4-Difluorophenyl)-3-pyridylcarboxaldehyde; 6-(3,4-Difluorophenyl)pyridine-3-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 6-(3,4-Difluorophenyl)-3-Pyridinecarbaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage or when opening sealed containers. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.