Description

Kx2-391 is a potent and selective small molecule inhibitor of Src kinase, a key enzyme involved in cellular signaling pathways. This compound is a critical research tool for studying the role of Src family kinases in various biological processes, including cell proliferation, differentiation, and survival. It is primarily utilized by researchers and scientists in the fields of oncology, cell biology, and biochemistry for target validation, signal transduction studies, and preclinical drug discovery.

Application

• Biomedical Research: Used as a selective Src kinase inhibitor in cellular and biochemical assays to investigate cancer mechanisms, tumor metastasis, and angiogenesis.
• Drug Discovery & Development: Serves as a lead compound or reference standard in high-throughput screening (HTS) and structure-activity relationship (SAR) studies for oncology targets.
• Signal Transduction Studies: A valuable tool for dissecting the role of Src family kinases in specific signaling cascades related to cell adhesion, migration, and cytoskeletal reorganization.
• Academic & Pharmaceutical R&D: Essential for basic research in universities and applied research in pharmaceutical companies focused on developing novel kinase-targeted therapies.

Basic Information

Product Name	Kx2-391
CAS No.	897016-82-9
Molecular Formula	C₂₀H₁₉N₅O₂
Molecular Weight	361.40 g/mol
Synonyms	KX2-391; KX2 391; KX 2-391; KX01; Tirbanibulin; (S)-N-Benzyl-2-(2,5-dihydro-1H-pyrrol-1-yl)-3-(1H-indazol-5-yl)propanamide; Src Kinase Inhibitor KX2-391; Benzyl N-[(2S)-1-oxo-1-[[(2,5-dihydro-1H-pyrrol-1-yl)]amino]-3-(1H-indazol-5-yl)propan-2-yl]carbamate
EINECS	Contact for details

Quality Control

Our Kx2-391 is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic data are provided for research and development purposes, supporting traceability and reproducibility in your experiments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.