Description

Prl-3 Inhibitor I is a potent and selective small molecule inhibitor of the Phosphatase of Regenerating Liver-3 (PRL-3) enzyme, a key target in oncology research. This compound is crucial for investigating the role of PRL-3 in cancer cell metastasis, proliferation, and signaling pathways. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on developing novel cancer therapeutics and understanding metastatic disease mechanisms.

Application

• Oncology Research & Drug Discovery: A critical tool for studying the biological function of the PRL-3 phosphatase and validating it as a therapeutic target in various cancer models.
• Cell Signaling Pathway Analysis: Used to dissect the downstream signaling cascades affected by PRL-3 inhibition, including those involved in cell motility and invasion.
• Metastasis Research: Employed in in vitro and in vivo studies to evaluate the compound's efficacy in inhibiting tumor cell migration and metastasis.
• Biochemical Assay Development: Serves as a reference standard in high-throughput screening (HTS) campaigns and enzymatic assays to identify new PRL-3 inhibitors.
• Preclinical Proof-of-Concept Studies: Supports lead optimization and preclinical evaluation of anti-metastatic agents targeting phosphatases.

Basic Information

Product Name	Prl-3 Inhibitor I
CAS No.	893449-38-2
Molecular Formula	C₁₉H₁₉N₃O₃S
Molecular Weight	369.44 g/mol
Synonyms	1-(2-Bromobenzyl)-3-(3-carbamoylphenyl)thiourea; PRL-3 Inhibitor; PRL3 Inhibitor I; 1-(2-Bromophenyl)methyl-3-(3-aminocarbonylphenyl)thiourea; BZ6; CAS 893449-38-2; PRL-3 Inhibitor, BZ6; N-(2-Bromobenzyl)-N'-(3-carbamoylphenyl)thiourea
EINECS	Contact for details

Quality Control

Our Prl-3 Inhibitor I is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. The product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to warm to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with reference structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in ethanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.