Description

4-Methyl-3,4-Dihydro-2H-1,4-Benzoxazine-6-Sulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to introduce the sulfonamide functional group, enabling the creation of novel compounds with targeted biological or material properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and fine chemicals. The compound, CAS NO 892948-94-6, is supplied under stringent quality control to ensure optimal performance in sensitive synthetic pathways.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing sulfonamide-based pharmacophores.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides where the benzoxazine-sulfonamide structure confers specific biological activity.
• Material Science Research: Employed as a monomer or cross-linking agent in the creation of specialty polymers with unique thermal or chemical resistance properties.
• Chemical Biology Probes: Utilized to create activity-based probes or affinity labels for studying enzyme function and protein interactions.
• Fine Chemical Production: Serves as a versatile intermediate for custom synthesis and the production of high-value, low-volume specialty chemicals.

Basic Information

Product Name	4-Methyl-3,4-Dihydro-2H-1,4-Benzoxazine-6-Sulfonyl Chloride
CAS No.	892948-94-6
Molecular Formula	C9H10ClNO3S
Molecular Weight	247.70 g/mol
Synonyms	6-(Chlorosulfonyl)-4-methyl-3,4-dihydro-2H-1,4-benzoxazine; 4-Methyl-2H-1,4-benzoxazine-6-sulfonyl chloride, 3,4-dihydro-; 3,4-Dihydro-4-methyl-2H-1,4-benzoxazine-6-sulfonyl chloride; 892948-94-6; 4-Methyl-3,4-dihydro-2H-benzo[b][1,4]oxazine-6-sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 4-Methyl-3,4-Dihydro-2H-1,4-Benzoxazine-6-Sulfonyl Chloride is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.