Description

2-Amino-6-(Trifluoromethyl)Nicotinaldehyde is a high-value, multi-functional pyridine derivative and a key building block in advanced organic synthesis. Its molecular structure, featuring both an aldehyde and an amino group adjacent to a trifluoromethyl substituent, makes it an exceptionally versatile intermediate for constructing complex heterocyclic systems. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex heterocyclic compounds, particularly for developing new active pharmaceutical ingredients (APIs) with potential therapeutic applications.
• Agrochemical Research: Used as a key building block for creating novel herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethyl group.
• Material Science: Serves as a monomer or functionalizing agent in the development of advanced polymers and specialty materials with tailored properties.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs) due to its chelating potential.
• Chemical Research & Development: A versatile scaffold in medicinal and combinatorial chemistry for library synthesis and structure-activity relationship (SAR) studies.

Basic Information

Product Name	2-Amino-6-(Trifluoromethyl)Nicotinaldehyde
CAS No.	890302-67-7
Molecular Formula	C7H5F3N2O
Molecular Weight	190.12 g/mol
Synonyms	6-(Trifluoromethyl)-2-aminonicotinaldehyde; 2-Amino-6-(trifluoromethyl)pyridine-3-carboxaldehyde; 3-Formyl-6-(trifluoromethyl)pyridin-2-amine; 2-Amino-3-formyl-6-(trifluoromethyl)pyridine; 6-Trifluoromethyl-2-aminonicotinaldehyde; 2-Amino-6-trifluoromethylnicotinaldehyde; 2-Pyridinamine, 3-formyl-6-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 2-Amino-6-(Trifluoromethyl)Nicotinaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and scale-up applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.