Description

1-Benzyl-3,5-Difluorobenzene is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. Its core value lies in the strategic placement of fluorine atoms and a benzyl group, which are critical for modulating the electronic properties, lipophilicity, and metabolic stability of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it serves as a key intermediate for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorine-containing drugs where it enhances bioavailability and metabolic resistance.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging fluorine's ability to improve biological activity and environmental persistence.
• Material Science Research: Serves as a monomer or precursor in the development of specialty polymers, liquid crystals, and organic electronic materials due to its aromatic and fluorinated structure.
• Chemical Synthesis & Catalysis: Acts as a versatile reagent in cross-coupling reactions (e.g., Suzuki, Heck) and as a ligand precursor in organometallic chemistry and catalysis development.
• Life Science & Diagnostics: Employed in the synthesis of fluorescent probes, biomarkers, and other molecular tools used in biochemical assays and diagnostic applications.

Basic Information

Product Name	1-Benzyl-3,5-Difluorobenzene
CAS No.	889945-56-6
Molecular Formula	C₁₃H₁₀F₂
Molecular Weight	204.22 g/mol
Synonyms	3,5-Difluorobenzylbenzene; (3,5-Difluorophenyl)methylbenzene; Benzyl-3,5-difluorobenzene; 1-(3,5-Difluorophenylmethyl)benzene; α-(3,5-Difluorophenyl)toluene
EINECS	Contact for details

Quality Control

Our 1-Benzyl-3,5-Difluorobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee consistency and support your regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area at room temperature (15-25°C). Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and potential concentration changes. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.