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(5-[2-(Trifluoromethyl)Phenyl]Pyridin-3-Yl)Methanol CAS NO 887974-28-9


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CAS No.:887974-28-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(5-[2-(Trifluoromethyl)Phenyl]Pyridin-3-Yl)Methanol is a high-value, multi-functional chemical intermediate characterized by its pyridine core and trifluoromethylphenyl substituent. This compound matters for its role as a critical building block in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its unique fluorine-containing aromatic system imparts desirable properties like metabolic stability and enhanced lipophilicity. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing new compounds with targeted biological activity.

Application

  • Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic areas.
  • Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group can enhance biological efficacy and environmental stability.
  • Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in catalytic systems and metal-organic frameworks (MOFs).
  • Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or fluorinated polymers.
  • Chemical Biology Probes: Utilized as a scaffold for developing fluorescent tags or molecular probes for diagnostic and research applications.

Basic Information

Product Name (5-[2-(Trifluoromethyl)Phenyl]Pyridin-3-Yl)Methanol
CAS No. 887974-28-9
Molecular Formula C13H10F3NO
Molecular Weight 253.22 g/mol
Synonyms 3-Pyridinemethanol, 5-[2-(trifluoromethyl)phenyl]-; [5-(2-Trifluoromethylphenyl)pyridin-3-yl]methanol; 5-(2-(Trifluoromethyl)phenyl)nicotinyl alcohol; 5-(α,α,α-Trifluoro-o-tolyl)pyridine-3-methanol; (5-(2-(Trifluoromethyl)phenyl)pyridin-3-yl)methanol; 3-Hydroxymethyl-5-(2-trifluoromethylphenyl)pyridine
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Quality Control

Our (5-[2-(Trifluoromethyl)Phenyl]Pyridin-3-Yl)Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Conforms to reference
Assay (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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