Description

[5-(2,4-Difluorophenyl)Pyridin-3-Yl]Methanol is a high-purity fluorinated pyridine derivative, serving as a critical advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis. Its value lies in its precise molecular architecture, which is essential for constructing complex molecules in medicinal chemistry and materials science. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, where the difluorophenyl and pyridine motifs contribute to biological activity and metabolic stability.
• Ligand & Catalyst Synthesis: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science: Employed in the research and development of organic electronic materials, such as components for OLEDs (Organic Light-Emitting Diodes) and conductive polymers.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.
• Academic & Industrial R&D: Utilized in research laboratories for method development, structure-activity relationship (SAR) studies, and exploring new chemical spaces.

Basic Information

Product Name	[5-(2,4-Difluorophenyl)Pyridin-3-Yl]Methanol
CAS No.	887974-19-8
Molecular Formula	C12H9F2NO
Molecular Weight	221.20 g/mol
Synonyms	(5-(2,4-Difluorophenyl)pyridin-3-yl)methanol; 3-Pyridinemethanol, 5-(2,4-difluorophenyl)-; 5-(2,4-Difluorophenyl)-3-pyridinemethanol; 5-(2,4-Difluorophenyl)nicotinyl alcohol; [5-(2,4-Difluorophenyl)-3-pyridyl]methanol; CAS 887974-19-8
EINECS	Contact for details

Quality Control

Our [5-(2,4-Difluorophenyl)Pyridin-3-Yl]Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced intermediate use. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.