Description

5-(2-Fluorophenyl)Nicotinaldehyde is a high-purity fluorinated nicotinaldehyde derivative, serving as a critical advanced pharmaceutical intermediate. Its core value lies in enabling the synthesis of complex molecules with enhanced biological activity and metabolic stability for modern drug discovery. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in developing new active ingredients for crop protection products, leveraging the fluorophenyl moiety for improved efficacy.
• Chemical Synthesis: Serves as a versatile precursor for creating complex heterocyclic compounds and functionalized pyridine derivatives.
• Material Science: Potential monomer or precursor for specialty polymers and advanced organic electronic materials.
• Academic & Contract Research: Employed in medicinal chemistry programs and process development within university and CRO/CMO settings.

Basic Information

Product Name	5-(2-Fluorophenyl)Nicotinaldehyde
CAS No.	887973-67-3
Molecular Formula	C12H8FNO
Molecular Weight	201.20 g/mol
Synonyms	5-(2-Fluorophenyl)pyridine-3-carbaldehyde; 3-Formyl-5-(2-fluorophenyl)pyridine; 5-(2-Fluorophenyl)-3-pyridinecarboxaldehyde; 2-Fluoro-5-(3-formylpyridin-5-yl)benzene; Nicotinaldehyde, 5-(2-fluorophenyl)-; Pyridine-3-carboxaldehyde, 5-(2-fluorophenyl)-
EINECS	Contact for details

Quality Control

Our 5-(2-Fluorophenyl)Nicotinaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect this light-sensitive material from moisture and atmospheric oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.