Description

3-(4-Bromo-Phenylamino)-Pyrrolidine-1-Carboxylic Acid tert-Butyl Ester is a high-value, protected pyrrolidine derivative featuring a brominated aniline moiety. This compound is a critical pharmaceutical intermediate and building block in organic synthesis, prized for its role in constructing complex molecular architectures. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the development of new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides due to its bioactive pyrrolidine core.
• Ligand and Catalyst Synthesis: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Employed in the creation of molecular probes for studying enzyme function and biological pathways.
• Material Science: Potential monomer or additive in the development of specialty polymers with unique optical or electronic properties.
• Academic & Contract Research: Essential reagent for methodological development and novel reaction exploration in university and CRO laboratories.

Basic Information

Product Name	3-(4-Bromo-Phenylamino)-Pyrrolidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	887578-11-2
Molecular Formula	C15H21BrN2O2
Molecular Weight	341.25 g/mol
Synonyms	tert-Butyl 3-[(4-bromophenyl)amino]pyrrolidine-1-carboxylate; 1-Boc-3-[(4-bromophenyl)amino]pyrrolidine; 1-(tert-Butoxycarbonyl)-3-[(4-bromophenyl)amino]pyrrolidine; 3-(4-Bromo-anilino)-1-Boc-pyrrolidine; N-(4-Bromophenyl)-1-Boc-3-aminopyrrolidine; 3-(4-Bromophenylamino)pyrrolidine-1-carboxylic acid tert-butyl ester; 1-Boc-3-(4-bromoanilino)pyrrolidine
EINECS	Contact for details

Quality Control

Our 3-(4-Bromo-Phenylamino)-Pyrrolidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, impurity profiles, and physical data. Our quality commitment supports cGMP and ISO standards for reliable use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.