Description

Clindamycin Pentadecanoate is a chemically modified ester derivative of the established antibiotic clindamycin. This compound is specifically engineered to enhance stability and modify the pharmacokinetic profile for advanced pharmaceutical research and development. It is a critical intermediate for medicinal chemists and formulation scientists working on novel drug delivery systems and prodrug strategies. The target industries include pharmaceutical R&D, contract manufacturing organizations (CMOs), and academic research institutions focused on antibiotic innovation.

Application

• Primary use as a key pharmaceutical intermediate in the synthesis of novel clindamycin analogs.
• Research and development of prodrug formulations aimed at improving bioavailability and targeted delivery.
• Development of long-acting injectable (LAI) antibiotic formulations for sustained release applications.
• Preclinical and clinical studies investigating modified antibiotic efficacy and safety profiles.
• Chemical reference standard for analytical method development and quality control in API manufacturing.
• Building block in medicinal chemistry for structure-activity relationship (SAR) studies.

Basic Information

Product Name	Clindamycin Pentadecanoate
CAS No.	1123211-67-5
Molecular Formula	C34H65ClN2O6S
Molecular Weight	665.41 g/mol
Synonyms	Clindamycin 2-Palmitate; Clindamycin Palmitate (common misnomer); Methyl 7-Chloro-6,7,8-trideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-L-threo-α-D-galacto-octopyranoside Pentadecanoate; (2S,4R)-N-[(1S,2S)-2-Chloro-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylthio)tetrahydro-2H-pyran-2-yl]propyl]-1-methyl-4-propyl-2-pyrrolidinecarboxamide Pentadecanoate; Clindamycin C15 Ester; Antibiotic L 12631 Derivative
EINECS	Contact for details

Quality Control

Our Clindamycin Pentadecanoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing specifications such as assay, related substances, and residual solvents are provided with every shipment. We support compliance with cGMP standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.