Description

Lincomycin Hydrochloride is a lincosamide antibiotic derived from *Streptomyces lincolnensis*. It is a critical active pharmaceutical ingredient (API) valued for its potent activity against Gram-positive bacteria, particularly in cases of penicillin resistance. This compound is essential for manufacturers in the pharmaceutical and veterinary medicine industries, where it is used to formulate injectable solutions, capsules, and topical preparations. Our high-purity grade ensures reliable performance and compliance with stringent global regulatory standards.

Application

• Pharmaceutical API: Primary use in the manufacture of human antibiotic formulations for treating serious infections caused by susceptible anaerobic bacteria and Gram-positive organisms.
• Veterinary Medicine: Key component in medicated feeds, injectables, and topical treatments for livestock, poultry, and companion animals to control bacterial infections.
• Research & Development: Serves as a standard reference compound and a key reagent in microbiological, biochemical, and pharmacological research studies.
• Antibiotic Susceptibility Testing: Used in clinical and diagnostic laboratories to prepare discs or media for antimicrobial susceptibility testing (AST).
• Biochemical Studies: Employed in research to study bacterial protein synthesis inhibition and mechanisms of antibiotic action and resistance.

Basic Information

Product Name	Lincomycin Hydrochloride
CAS No.	17017-22-0
Molecular Formula	C18H34N2O6S·HCl
Molecular Weight	461.01 g/mol
Synonyms	Lincomycin HCl; Lincomycin Monohydrochloride; Lincocin; Lincolnensin; (2S,4R)-N-[(1R,2R)-2-Hydroxy-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-methylsulfanyloxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide hydrochloride; U-10149A; NSC 70731; Antibiotic U 10149A
EINECS	241-088-1

Quality Control

Our Lincomycin Hydrochloride is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting parameters such as assay, related substances, residual solvents, and microbiological quality. We support compliance with major pharmacopoeial standards (e.g., USP, EP) and relevant GMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (Karl Fischer)	≤ 6.0%
Residue on Ignition	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 1.0%
Heavy Metals	≤ 20 ppm
Microbial Limits	Conforms to EP/USP requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.