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Lincomycin CAS NO 154-21-2


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CAS No.:154-21-2

Grade:Pharmacy Grade

Content:99.0%

Brand:Customizable

Packaging:Customizable

Description

Lincomycin is a lincosamide antibiotic produced by *Streptomyces lincolnensis*. This compound is valued for its potent activity against Gram-positive bacteria, particularly anaerobic organisms. It is a critical active pharmaceutical ingredient (API) for the formulation of veterinary and human pharmaceutical products. Key industries requiring this material include pharmaceutical manufacturing, veterinary medicine, and academic research.

Application

  • Veterinary Pharmaceutical Formulations: Primary use as an injectable or oral antibiotic for treating infections in livestock and companion animals.
  • Human Pharmaceutical Intermediates: Serves as a key starting material or intermediate in the synthesis of semi-synthetic derivatives like clindamycin.
  • Microbiological Research: Used as a selective agent in culture media and for studying bacterial resistance mechanisms in laboratory settings.
  • Aquaculture: Employed in medicated feeds to control bacterial diseases in farmed fish and shellfish.
  • Reference Standard: Sourced by analytical laboratories for use as a high-purity calibration standard in HPLC and other assay methods.

Basic Information

Product Name Lincomycin
CAS No. 154-21-2
Molecular Formula C18H34N2O6S
Molecular Weight 406.54 g/mol
Synonyms Lincomycin A; Lincomycin Hydrochloride (salt form); Lincocin; Lincolnensin; Cillinicina; U-10149; (2S,4R)-N-[(1R,2R)-2-Hydroxy-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylsulfanyl)oxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide
EINECS 205-819-3

Quality Control

Our Lincomycin is manufactured and tested under a strict quality management system. Each batch is analyzed to meet high-purity standards suitable for pharmaceutical applications, with testing typically including identification, assay, and impurity profile. A comprehensive Certificate of Analysis (COA) documenting all test results is provided with every shipment to ensure traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to reference spectrum
Identification (HPLC) Retention time matches reference standard
Assay (HPLC) ≥ 98.0% (on anhydrous basis)
Water Content (KF) ≤ 5.0%
Residue on Ignition ≤ 0.5%
Heavy Metals ≤ 20 ppm
Related Substances (HPLC) Total impurities ≤ 2.0%
Specific Rotation +137° to +145° (c=1 in water)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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