Description

7-Chlorolincomycin Hydrochloride is a chemically modified derivative of the lincosamide antibiotic, lincomycin, designed for enhanced potency and research utility. This compound is critical for pharmaceutical R&D, particularly in the study of antibiotic mechanisms, resistance, and the development of novel therapeutic agents. It serves as a key intermediate and reference standard for researchers and manufacturers in the pharmaceutical, biotechnology, and academic sectors focused on antimicrobial development.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of advanced lincosamide antibiotic derivatives and novel drug candidates.
• Biochemical Research: Used as a reference standard and active agent in studies investigating bacterial protein synthesis inhibition, ribosomal targeting, and antibiotic mode of action.
• Microbiology & Antimicrobial Studies: Employed in in vitro assays to evaluate potency against Gram-positive bacteria and to study mechanisms of bacterial resistance.
• Analytical Standard: Provides a high-purity benchmark for quality control (QC) and analytical method development (e.g., HPLC, LC-MS) in pharmaceutical manufacturing.
• Veterinary Pharmaceutical Development: Investigated for potential applications in developing antimicrobial treatments for animal health.

Basic Information

Product Name	7-Chlorolincomycin Hydrochloride
CAS No.	17431-55-9
Molecular Formula	C18H33ClN2O6S • HCl
Molecular Weight	461.85 g/mol (as hydrochloride)
Synonyms	Clindamycin Impurity F; 7-Chloro-7-deoxylincomycin Hydrochloride; 7(S)-Chlorolincomycin Hydrochloride; Lincomycin, 7-chloro-, hydrochloride; U-24729A; Antibiotic U-24729A; 7-Cl-Lincomycin HCl
EINECS	Contact for details

Quality Control

Our 7-Chlorolincomycin Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and tests for residual solvents and related substances. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and pharmaceutical intermediate standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.