Description

Clindamycin B is a semi-synthetic lincosamide antibiotic derived from the natural compound lincomycin. This potent antibacterial agent is valued for its efficacy against a broad spectrum of anaerobic bacteria and Gram-positive aerobes. It is a critical intermediate and reference standard in the pharmaceutical industry for the research, development, and quality control of antibiotic formulations. Professionals in pharmaceutical R&D, analytical laboratories, and chemical synthesis rely on high-purity Clindamycin B to ensure product efficacy and regulatory compliance.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of Clindamycin hydrochloride and other clindamycin salts for final dosage forms.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control testing of antibiotic products via HPLC, LC-MS, or other chromatographic techniques.
• Antibacterial Research: Employed in microbiological and pharmacological studies to investigate mechanisms of action, resistance patterns, and the development of new antimicrobial agents.
• Active Pharmaceutical Ingredient (API) Manufacturing: Integral to the production chain of finished antibiotic drugs under current Good Manufacturing Practice (cGMP) standards.
• Veterinary Medicine: Applied in the development of antibacterial treatments for animal health.

Basic Information

Product Name	Clindamycin B
CAS No.	18323-43-8
Molecular Formula	C18H33ClN2O5S
Molecular Weight	424.98 g/mol
Synonyms	7(S)-Chloro-7-deoxylincomycin; U-28508; 7-Chloro-7-deoxylincomycin; Methyl 7-chloro-6,7,8-trideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-L-threo-α-D-galacto-octopyranoside; Clindamycin B Base
EINECS	Contact for details

Quality Control

Our Clindamycin B is manufactured and tested to meet high-purity standards suitable for pharmaceutical research and development. Quality is assured through a comprehensive battery of analytical tests, including identification, assay, and impurity profiling. While specific grades (e.g., USP, EP) are available, all batches are supported by a detailed Certificate of Analysis (COA) documenting purity, related substances, and residual solvents. We adhere to a rigorous quality management system to ensure batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.