Description

2-Bromo-1-Fluoro-4-(Methoxymethyl) Benzene is a high-purity, multi-functional halogenated aromatic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring bromine, fluorine, and a methoxymethyl group, makes it a versatile intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and industrial R&D departments engaged in pharmaceutical development, agrochemical discovery, and materials science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic cores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the halogen and ether functionalities are critical for bioactivity.
• Liquid Crystal & OLED Materials: Serves as a building block for advanced electronic materials, where its aromatic and halogenated structure contributes to desired electronic and physical properties.
• Cross-Coupling Reactions: The bromine atom is an excellent handle for metal-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Negishi) to form new carbon-carbon bonds.
• Functional Group Transformation: The methoxymethyl group can be used as a protected alcohol or aldehyde equivalent, offering strategic flexibility in multi-step syntheses.
• Chemical Research & Development: Employed in academic and industrial labs for exploring new synthetic methodologies and creating novel chemical entities for screening.

Basic Information

Product Name	2-Bromo-1-Fluoro-4-(Methoxymethyl) Benzene
CAS No.	887268-22-6
Molecular Formula	C8H8BrFO
Molecular Weight	219.05 g/mol
Synonyms	1-Bromo-2-fluoro-5-(methoxymethyl)benzene; 2-Bromo-1-fluoro-4-methoxymethylbenzene; 4-(Methoxymethyl)-2-bromofluorobenzene; Benzene, 2-bromo-1-fluoro-4-(methoxymethyl)-; 2-Fluoro-5-(methoxymethyl)bromobenzene; 5-(Methoxymethyl)-2-fluorobromobenzene; 887268-22-6
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-Fluoro-4-(Methoxymethyl) Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥97.0% (Standard Grade)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.