Description

Ac-Gly-Boropro CAS NO 886992-99-0 is a specialized boron-containing amino acid derivative, designed for advanced research and development applications. This compound is valued for its unique molecular structure, which incorporates a boroproline moiety, making it a critical building block in medicinal chemistry and proteomics. It is primarily utilized by pharmaceutical researchers, biochemists, and chemical manufacturers focused on developing novel enzyme inhibitors and targeted therapeutic agents.

Application

• As a key intermediate in the synthesis of novel pharmaceutical candidates, particularly protease inhibitors.
• In biochemical research for studying enzyme-substrate interactions and reaction mechanisms.
• For the development of boron neutron capture therapy (BNCT) agents and other targeted cancer therapeutics.
• As a specialized building block in peptide and peptidomimetic chemistry for drug discovery programs.
• In proteomics research as a tool compound for labeling and analysis.
• For the preparation of chemical probes used in molecular biology and diagnostic assay development.

Basic Information

Product Name	Ac-Gly-Boropro
CAS No.	886992-99-0
Molecular Formula	C9H15BN2O4
Molecular Weight	226.04 g/mol
Synonyms	N-Acetylglycylboroproline; Ac-Gly-BoroPro; (S)-1-((2-Acetamidoacetyl)amino)-3-(dihydroxyboryl)propyl)pyrrolidine-2-carboxylic acid; Bortezomib Intermediate Analog; Boronic Acid Peptide Derivative; Proteasome Inhibitor Building Block; Ac-Gly-BoroPro-OH
EINECS	Contact for details

Quality Control

Our Ac-Gly-Boropro is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and specific tests for residual solvents and heavy metals. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under a dry, inert atmosphere to maintain stability and purity. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.