Description

3-Chloro-4-(Trifluoromethoxy)Benzenesulfonyl Chloride is a high-purity, multi-functional sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both chloro and trifluoromethoxy substituents, makes it an exceptionally versatile intermediate for introducing specific functionalities into target molecules. This compound is primarily sought after by R&D and production chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients, where its sulfonyl chloride group enables efficient coupling reactions.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used to construct novel herbicides, fungicides, and insecticides that benefit from the enhanced metabolic stability imparted by the trifluoromethoxy group.
• Material Science: Building block for creating specialized polymers and functional materials with tailored surface properties.
• Dye and Pigment Manufacturing: Intermediate in the production of high-performance, light-fast dyes and pigments.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing complex ligands used in catalytic systems.
• Custom Synthesis and Contract Manufacturing: Essential reagent for research organizations and CROs/CMOs developing proprietary compounds.

Basic Information

Item	Details
Product Name	3-Chloro-4-(Trifluoromethoxy)Benzenesulfonyl Chloride
CAS No.	886762-48-7
Molecular Formula	C7H3Cl2F3O3S
Molecular Weight	303.06 g/mol
Synonyms	3-Chloro-4-(trifluoromethoxy)benzene-1-sulfonyl chloride; 4-Chloro-α,α,α-trifluoro-3-methoxybenzenesulfonyl chloride; 3-Chloro-4-trifluoromethoxybenzenesulfonyl chloride; 1-Chloro-2-(trifluoromethoxy)-4-(chlorosulfonyl)benzene; 886762-48-7; 3-Chloro-4-(trifluoromethoxy)phenylsulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-4-(Trifluoromethoxy)Benzenesulfonyl Chloride is manufactured under strict quality management protocols. We employ advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee it meets your precise research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases, oxidizing agents, and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.