Description

3-Bromo-2-Hydroxy-5-(Trifluoromethyl)Benzaldehyde is a versatile and highly functionalized aromatic aldehyde building block. Its unique molecular structure, featuring bromo, hydroxy, and trifluoromethyl substituents, makes it a critical intermediate for synthesizing complex molecules with tailored properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries. It enables the construction of advanced chemical libraries and active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, liquid crystals, and advanced polymers due to its electron-withdrawing and steric properties.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	3-Bromo-2-Hydroxy-5-(Trifluoromethyl)Benzaldehyde
CAS No.	886762-43-2
Molecular Formula	C8H4BrF3O2
Molecular Weight	269.02 g/mol
Synonyms	5-(Trifluoromethyl)-3-bromosalicylaldehyde; 3-Bromo-5-(trifluoromethyl)salicylaldehyde; 2-Hydroxy-3-bromo-5-(trifluoromethyl)benzaldehyde; 3-Bromo-2-hydroxy-5-trifluoromethylbenzaldehyde; Benzaldehyde, 3-bromo-2-hydroxy-5-(trifluoromethyl)-; 886762-43-2; Aldehyde intermediate 886762-43-2
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Hydroxy-5-(Trifluoromethyl)Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to cGMP and ISO standards ensures reliable supply for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and light-sensitive (store away from light). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.