Description

3-Fluoro-2-Trifluoromethyl-Isonicotinic Acid is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and trifluoromethyl groups, is engineered to impart enhanced metabolic stability, lipophilicity, and bioavailability to target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), especially in kinase inhibitors and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine motifs contribute to efficacy and environmental persistence.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of fluorinated organic electronic materials and liquid crystals.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up services for specialized chemical entities.

Basic Information

Item	Details
Product Name	3-Fluoro-2-Trifluoromethyl-Isonicotinic Acid
CAS No.	886510-09-4
Molecular Formula	C7H3F4NO2
Molecular Weight	209.10 g/mol
Synonyms	3-Fluoro-2-(trifluoromethyl)isonicotinic acid; 3-Fluoro-2-(trifluoromethyl)pyridine-4-carboxylic acid; 4-Pyridinecarboxylic acid, 3-fluoro-2-(trifluoromethyl)-; 2-Trifluoromethyl-3-fluoro-isonicotinic acid; 3-Fluoro-2-trifluoromethylpyridine-4-carboxylic acid; 886510-09-4; AI3-34050
EINECS	Contact for details

Quality Control

Our 3-Fluoro-2-Trifluoromethyl-Isonicotinic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its acidic nature, keep away from strong bases and incompatible materials. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.