Description

2-(3-(Trifluoromethyl)Phenyl)Pyridin-3-Amine is a high-purity, advanced pharmaceutical intermediate characterized by its pyridine core and trifluoromethylphenyl substituent. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and development for oncology, central nervous system (CNS) disorders, and other specialized treatments.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates and novel small molecule therapeutics.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the biological activity of the trifluoromethyl group.
• Material Science: Serves as a precursor for functionalized ligands and organic electronic materials due to its aromatic structure.
• Academic & R&D: Employed in chemical research for studying structure-activity relationships (SAR) and developing new synthetic methodologies.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for scale-up and cGMP production of clinical trial materials.

Basic Information

Product Name	2-(3-(Trifluoromethyl)Phenyl)Pyridin-3-Amine
CAS No.	886508-01-6
Molecular Formula	C12H9F3N2
Molecular Weight	238.21 g/mol
Synonyms	3-Amino-2-[3-(trifluoromethyl)phenyl]pyridine; 2-(3-(Trifluoromethyl)phenyl)-3-pyridinamine; 2-(α,α,α-Trifluoro-m-tolyl)-3-aminopyridine; 886508-01-6; 3-Pyridinamine, 2-[3-(trifluoromethyl)phenyl]-; 2-(3-Trifluoromethylphenyl)pyridin-3-ylamine
EINECS	Contact for details

Quality Control

Our 2-(3-(Trifluoromethyl)Phenyl)Pyridin-3-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to ensure product integrity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.