Description

2,2,3,3,3-Pentafluoro-1-Pyridin-4-Yl-Ethanol CAS NO 886496-24-8 is a high-value fluorinated pyridine derivative, a key building block in advanced organic synthesis. Its unique structure, combining a pentafluoroethyl alcohol moiety with a pyridine ring, makes it a critical intermediate for developing novel compounds with enhanced properties. This chemical is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to create active ingredients with improved metabolic stability, bioavailability, and lipophilicity.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting central nervous system (CNS) disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used to develop advanced herbicides, fungicides, and insecticides, where the fluorine atoms contribute to increased biological activity, stability, and membrane permeability.
• Liquid Crystal Materials: Acts as a fluorinated component in the production of high-performance liquid crystals for display technologies, improving dielectric anisotropy and thermal stability.
• Organic Electronics: Employed in the research and development of novel organic semiconductors and electron-transport materials for OLEDs and photovoltaic cells.
• Chemical Research & Development: A versatile building block in academic and industrial R&D for exploring new fluorination strategies and creating complex molecular architectures.
• Coordination Chemistry & Ligand Design: The pyridine nitrogen and alcohol functional group make it a candidate for designing novel ligands in catalytic and metal-organic framework (MOF) synthesis.

Basic Information

Product Name	2,2,3,3,3-Pentafluoro-1-Pyridin-4-Yl-Ethanol
CAS No.	886496-24-8
Molecular Formula	C7H4F5NO
Molecular Weight	213.11 g/mol
Synonyms	4-(2,2,3,3,3-Pentafluoro-1-hydroxyethyl)pyridine; 4-(Pentafluoroethyl)pyridin-4-ylmethanol; 1-(Pyridin-4-yl)-2,2,3,3,3-pentafluoroethan-1-ol; Pentafluoroethyl-4-pyridylmethanol; α,α,β,β,β-Pentafluoro-4-pyridineethanol; 886496-24-8; 4-(1-Hydroxy-2,2,3,3,3-pentafluoroethyl)pyridine
EINECS	Contact for details

Quality Control

Every batch of 2,2,3,3,3-Pentafluoro-1-Pyridin-4-Yl-Ethanol is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot upon request. Our quality protocols are designed to support cGMP (current Good Manufacturing Practice) standards for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.