Description

2,2,3,3,3-Pentafluoro-1-Pyridin-3-Yl-Propanol is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, combining a pentafluoroalkyl chain with a pyridine heterocycle, makes it an essential intermediate for developing novel compounds with enhanced properties. This product is primarily targeted at R&D and production teams in the pharmaceutical, agrochemical, and specialty materials industries seeking to incorporate fluorine for improved bioactivity, stability, or surface characteristics.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in creating advanced fluorinated pesticides, herbicides, and fungicides where the fluorine atoms enhance lipophilicity, metabolic stability, and membrane penetration.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, improving dielectric anisotropy and thermal stability.
• Polymer & Surface Modifier: Incorporated into specialty polymers to impart oil- and water-repellent (omniphobic) surface properties for coatings and textiles.
• Ligand & Catalyst Development: Utilized in organometallic chemistry to create novel fluorinated ligands for catalysis, potentially enhancing reaction selectivity and efficiency.
• Fluorinated Probe & Sensor Chemistry: Acts as a building block for developing fluorescent dyes, MRI contrast agents, and biochemical probes used in diagnostic imaging and research.

Basic Information

Product Name	2,2,3,3,3-Pentafluoro-1-Pyridin-3-Yl-Propanol
CAS No.	886496-18-0
Molecular Formula	C8H6F5NO
Molecular Weight	227.13 g/mol
Synonyms	3-(2,2,3,3,3-Pentafluoro-1-hydroxypropyl)pyridine; 3-(1-Hydroxy-2,2,3,3,3-pentafluoropropyl)pyridine; 1-Pyridin-3-yl-2,2,3,3,3-pentafluoropropan-1-ol; Pentafluoropropyl-3-pyridylmethanol; 886496-18-0; 3-Pyridylpentafluoropropanol
EINECS	Contact for details

Quality Control

Our 2,2,3,3,3-Pentafluoro-1-Pyridin-3-Yl-Propanol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production adheres to cGMP principles where applicable, ensuring reliability for sensitive pharmaceutical and agrochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.