Description

2,2,3,3,3-Pentafluoro-1-Phenyl-1-Pyridin-2-Yl-Ethanol is a high-value fluorinated pyridine derivative, a key building block in advanced organic synthesis. Its unique structure, featuring both pentafluoroalkyl and aromatic heterocyclic groups, makes it an essential intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the introduction of fluorine atoms can significantly improve efficacy and environmental profile.
• Ligand Synthesis for Catalysis: Serves as a starting material for constructing sophisticated chiral and non-chiral ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the creation of specialty polymers, liquid crystals, and organic electronic materials that benefit from the unique electronic properties of the fluorinated segment.
• Fluorine Chemistry & Library Synthesis: A valuable scaffold for medicinal and combinatorial chemistry to generate diverse compound libraries for high-throughput screening.

Basic Information

Product Name	2,2,3,3,3-Pentafluoro-1-Phenyl-1-Pyridin-2-Yl-Ethanol
CAS No.	886496-10-2
Molecular Formula	C13H8F5NO
Molecular Weight	289.20 g/mol
Synonyms	α-(Pentafluoroethyl)-α-phenyl-2-pyridinemethanol; 1-Phenyl-1-(2-pyridinyl)-2,2,3,3,3-pentafluoroethanol; 2-Pyridinemethanol, α-(pentafluoroethyl)-α-phenyl-; 1-(Pyridin-2-yl)-2,2,3,3,3-pentafluoro-1-phenylethanol; Pentafluoroethyl(phenyl)(pyridin-2-yl)methanol
EINECS	Contact for details

Quality Control

Our 2,2,3,3,3-Pentafluoro-1-Phenyl-1-Pyridin-2-Yl-Ethanol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our standard grade meets high-purity research requirements, and custom synthesis to specific purity grades (e.g., >98%, >99%) is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.