Description

5-Bromo-2-Ethoxy-3-Fluoro-Pyridine is a high-purity, multi-functional halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique substitution pattern, which allows for selective functionalization and incorporation into complex molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, leveraging its halogenated pyridine core for bioactivity.
• Material Science Research: Serves as a precursor for functionalized ligands and organic electronic materials.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring specific halogenated heterocycles.

Basic Information

Product Name	5-Bromo-2-Ethoxy-3-Fluoro-Pyridine
CAS No.	886373-20-2
Molecular Formula	C7H7BrFNO
Molecular Weight	220.04 g/mol
Synonyms	3-Fluoro-5-bromo-2-ethoxypyridine; 2-Ethoxy-3-fluoro-5-bromopyridine; 5-Bromo-3-fluoro-2-ethoxypyridine; 886373-20-2; Pyridine, 5-bromo-2-ethoxy-3-fluoro-; 5-Bromo-2-ethoxy-3-fluoropyridine
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Ethoxy-3-Fluoro-Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP and ISO 9001 guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under an inert atmosphere for long-term storage to prevent degradation. Keep away from strong acids/bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.