Description

3-Methyl-4-Trifluoromethoxy-Pyridine-2-Carbaldehyde is a high-purity, multi-functional pyridine derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in the unique trifluoromethoxy and aldehyde functional groups, which enable precise molecular construction for high-performance materials and active compounds. This product is essential for R&D and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce fluorinated motifs and reactive handles into complex molecules.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates targeting CNS disorders, inflammation, and infectious diseases.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and transition metal catalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials that require fluorinated aromatic components.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Item	Details
Product Name	3-Methyl-4-Trifluoromethoxy-Pyridine-2-Carbaldehyde
CAS No.	886372-33-4
Molecular Formula	C8H6F3NO2
Molecular Weight	205.14 g/mol
Synonyms	3-Methyl-4-(trifluoromethoxy)picolinaldehyde; 2-Formyl-3-methyl-4-(trifluoromethoxy)pyridine; 4-(Trifluoromethoxy)-3-methylpyridine-2-carboxaldehyde; 3-Methyl-4-trifluoromethoxypyridine-2-carbaldehyde; 2-Pyridinecarboxaldehyde, 3-methyl-4-(trifluoromethoxy)-; 886372-33-4
EINECS	Contact for details

Quality Control

Every batch of 3-Methyl-4-Trifluoromethoxy-Pyridine-2-Carbaldehyde is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting purity, identity, and impurity profiles as determined by HPLC, GC, NMR, and other relevant techniques.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. This compound is easily oxidized; ensure containers are sealed immediately after use to minimize exposure to air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.