Description

4-Fluoro-Pyridine-2-Carboxylic Acid Methyl Ester is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its structure combines a reactive ester group with a fluorine-substituted pyridine ring, making it an essential intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and metal complexation.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials for electronic or optical applications.
• Chemical Biology Probes: Utilized to develop fluorinated molecular probes and tags for studying biological systems and mechanisms.

Basic Information

Product Name	4-Fluoro-Pyridine-2-Carboxylic Acid Methyl Ester
CAS No.	886371-79-5
Molecular Formula	C7H6FNO2
Molecular Weight	155.13 g/mol
Synonyms	Methyl 4-fluoropyridine-2-carboxylate; 4-Fluoropyridine-2-carboxylic acid methyl ester; 2-Pyridinecarboxylic acid, 4-fluoro-, methyl ester; Methyl 4-fluoro-2-pyridinecarboxylate; 4-Fluoro-2-(methoxycarbonyl)pyridine
EINECS	Contact for details

Quality Control

Our 4-Fluoro-Pyridine-2-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for research and regulated synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.